Ammonium chloride catalyzed microwave-assisted synthesis of tetrahydrobenzo[b]pyrans
Authors
Abstract:
In the present work, we have developed a mild, efficient, and environmentally benign method for the synthesis of tetrahydrobenzo[b]pyran derivatives via a three-component cyclocondensation of aldehydes, malononitrile and dimedone utilizing ammonium chloride as a simple, easily available and cost effective catalyst under microwave irradiation. This method has several attracting features such as simple experimental set up, easy work-up procedure, high conversions and short reaction times affording the products in moderate to excellent yield.
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Journal title
volume 6 issue 2
pages 189- 192
publication date 2016-06-01
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